What is the hormone secreted by the stomach in the human body? .. And what is his job

What is the hormone secreted by the stomach in the human body?
What is the hormone secreted by the stomach in the human body?


*** Hormone secreted by the stomach in the human body

stomach It works on larger proteins to turn proteins into smaller shapes.


The hormone gastrin is produced in the bloodstream during the entry of food into the stomach and is transferred by the circulatory system to the stomach cells located in the stomach wall, which causes the secretion of intestinal juice. It also kills bacteria inside food, and produces pecin, which breaks down protein, and gastrin increases the movement of the stomach, which helps in flipping food and emptying the stomach. In addition, gastrin increases the movement of the small intestine and the gallbladder.

The medical importance of gastrin is when there are tumors in the pancreatic cells, which are called gastrin tumors, which are secreted inside the body in large quantities than the normal rate. Gastrinoma is a component of multiple endocrine neoplasia type 1 (MEN1) syndrome, a rare disorder known as Zollinger-Ellison syndrome. The treatment for this rare disorder is surgical removal of the tumor in order to treat the patient with a drug that inhibits gastric acid secretion.


*** What is the hormone responsible for the digestion of proteins in the stomach?


One of the first hormones responsible for the digestion of proteins is the secretion of saliva by the salivary glands as a result of the response to the stimuli provided by the food in preparation for the completion of the digestion process, and the stomach then begins to produce hydrochloric acid to help digest food, where the auxiliary movements to complete the digestion process such as movements of the esophagus and the movements of other organs Within the digestive system, where all of them are subject to the instructions of the brain, where the brain sends signals to carry out the movements of the organs even while the stomach is filled with food, and the signals of the brain determine the feeling of satiety, and there are three overlapping stages in order to control the stomach, and they are the following:


head stage.

stomach stage.

intestinal stage.

All of these stages require many enzymes that are under neuronal control.


*** Gastrin treatment.


In order to treat excessive gastrin, the doctor will ask about the signs, symptoms and medical history of the person and will do many methods for treating excessive gastrin, which are the following steps:


Blood tests

A blood sample is analyzed to see if a person has high levels of gastrin, as a high level of gastrin may indicate the presence of tumors in the pancreas or in the duodenum, which means other conditions where when gastrin rises, this means that the stomach does not secrete In this case, you should take medications that reduce acidity, such as proton pump inhibitors.


You need to fast

When you have an excess of the gastrin hormone, you must fast and reduce the intake of medications to reduce acidity in order to accurately know the level of gastrin in the body, because the ratio of gastrin can change easily and this may make a person take the test several times.


secretion stimulation test

In order for the doctor to test the level of gastrin in the body, the doctor gives the person an injection of the secretin hormone in order to accurately measure the level of gastrin in the body.


upper gastrointestinal endoscopy

After the doctor anesthetizes the patient, the upper gastrointestinal endoscopy is performed by inserting a very thin and flexible instrument equipped with a light and video camera called the endoscope. It enters the body from the bottom of the throat to the stomach and duodenum to search for the presence of any ulcers, and through the endoscope the doctor can Removing a sample of tissue, called a duodenal biopsy, to help detect gastrin tumors so your doctor will ask you not to eat anything after midnight the night before this test.


Endoscopic Ultrasound

Before doing this test, the doctor examines the stomach, duodenum, and pancreas with an endoscope equipped with ultrasound, to do a precise examination, which facilitates the discovery of tumors, and it also facilitates the removal of a sample of tissues called biopsy by this endoscope. In order to do this test, fasting may also be required. From midnight the night before and the test is done after anesthesia of the patient.


Imaging tests

One of the treatment methods used for excessive gastrin is the use of imaging techniques such as the use of a nuclear scanning technique called scintigraphy, and this test uses some radioactive tracers to locate the tumor, and imaging tests include many types such as ultrasound and computerized tomography (CT) tests. Magnetic resonance imaging (MRI) and Ga-DOTATATE PET-CT scanning.


Oncology treatment

Tumors caused by excessive gastrin may in some cases require surgical intervention to remove tumors, but most often these tumors may be small in size but difficult to locate, and surgical removal of the tumor may be the best solution for a single tumor, but for multiple tumors In the liver that affects the liver, the treating doctor may recommend removing only one large tumor. In some other cases, doctors recommend other treatment methods in order to control the growth of the tumor, including the following methods:


Remove as much of the liver tumor as possible.

Attempting to destroy a tumor by cutting off the blood supply or by using heat to destroy cancer cells.

Injecting drugs directly into the tumor in order to relieve symptoms of cancer.

Use of chemotherapy to try to slow the growth of the tumor.

Performing a liver transplant.


*** The hormone gastrin causes hunger.


Gastrin is secreted in the stomach and small intestine during eating. Gastrin stimulates the secretion of hydrochloric acid and pepsin inside the stomach, which helps to speed up the completion of the digestive process. Gastrin stimulates glucagon, a hormone that works with insulin to regulate blood sugar, and the brain sends a signal to The stomach in order to secrete the hormone gastrin through the walls of the stomach, during meals, especially meals that contain proteins.

It is possible that the production of the hormone gastrin through the hormone somatostatin, which is secreted by the pancreas during emptying the stomach of food, and then the pH level is low inside the stomach and thus the stomach becomes more acidic.


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