All you need to know about Pfizer's anti-coronavirus pills

All you need to know about Pfizer's anti-coronavirus pills


The US Food and Drug Administration has approved a new drug from Pfizer, a pill taken orally, for emergency use in moderate and severe cases of Covid 19 disease caused by the Corona virus.

The drug, Paxlovid, is the first home remedy for Covid-19 to be approved by the US Food and Drug Administration.

Paxilovid, a combination of the antiviral drugs nimatelvir and ritonavir, is the second oral drug approved by the United States for use in patients with mild symptoms.

Pfizer's Paxilvid contains nirmatilvir and ritonavir. While nirmatilvir prevents the replication of the coronavirus by inhibiting the viral protein, ritonavir slows down the breakdown of nirmatilvir so that it stays in the body longer at higher concentrations.

Paxlovid is given as three tablets (two nirmatrelvir tablets and one ritonavir tablet taken together by mouth) twice daily for five days, which means a total of 30 tablets, but it is not recommended to use the medicine for more than five consecutive days.

The US Food and Drug Administration (FDA) authorized Paxlovid to treat mild to moderate COVID-19 in adults and children (12 years and over) on December 22, 2021, and stated that Paxlovid should be started as soon as possible after COVID-19 is diagnosed and within 5 days of symptoms appearing. .


*** Possible side effects of Paxolvid

The US Food and Drug Administration has warned that Paxlovid should not be used for pre-exposure or post-exposure prophylaxis, nor is it authorized to start treatment for those who need hospitalization due to severe or critical corona, and said that Paxlovid is not a substitute for vaccination.

Paxlovid may cause side effects such as impaired taste, diarrhea, high blood pressure and muscle pain, and the US Food and Drug Administration warns that using Paxlovid at the same time with some other medications may lead to possible drug interactions.

Ritonavir cannot be taken simultaneously with high blood pressure medicine and many other medicines.

According to Pfizer, clinical trials have shown that Paxlovid can reduce the risk of hospitalization and death by 88 percent in patients who took the drug within five days of onset of symptoms compared to those who took a placebo.


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